Malcolm in the middle

Aaron Paul auditioned for the role of Francis but lost. He would later be cast in 'Breaking Bad', which also starred Bryan Cranston.

On the show, Reese is the second oldest brother of Malcolm, but in real life, Justin Berfield (Reese) is less than three months younger than Frankie Muniz (Malcolm).

The show featured no laugh track, which was unusual for a live-action sitcom.