Grimm

It was revealed at Comic Con that actual descendants of the Brothers Grimm reside in Portland. The producers had no idea until a member in the audience told them.

Whenever the episode includes a room number (hotel room, hospital ward or bed) or address, the number is the combination of the number of the season and of the episode

According to Kelly Burkhardt, the Grimm trait is not strictly hereditary. Some offspring of Grimms have it and others don't. Girls also realize it earlier than boys.