Desperate Housewives

Originally started off as a comedy pilot, and was rejected by every network including Lifetime and HBO. ABC expressed an interest, and it was retooled to its current format of a dark comedy/drama.

Teri Hatcher broke two ribs filming the scene where she stumbles into a wedding cake and insisted they didn't stop production.

Teri Hatcher is the first person to win the Screen Actors Guild Award for Outstanding Performance by a Female Actor in a Comedy Series for a show that has not yet completed its first season.