'Frenzy' is set in London in the early 1970s. The film begins with the discovery of a corpse of a naked woman on the Thames River in broad daylight. She has a tie knotted in her throat and there are indications that she has been raped and killed. A sex criminal known as the The necktie Muderer is on the loose and has the police completely blocked and bewildered as several murders of these characteristics have already occurred and no one has a valid answer. The protagonist of the film Richard Blaney, played by Jon Finch, is fired from the bar where he used to work since his boss accuses him of having stolen liquors from the establishment. Later he goes to dinner with his ex-wife, Brenda Blaney, at a restaurant where they have a big discussion. The next day, Richard goes to his ex-wife's office to find his lifeless body strangled. This will make the police believe that he is the murderer and imprison him. During the movie Blaney will try to prove that he has not done anything wrong.

The film is directed by Alfred Hitchcock and written by Anthony Shaffer based on the novel 'Goodbye Piccadilly, Farewell Leicester Square' by Arthur La Bern. The star Jon Finch, Barry Foster, Barbara Leigh-Hunt, Anna Massey and Alec McCowen among others.