Bob is a grungy ringleader and jittery mastermind of a junkie crew. With his frustrated wife Dianne, his loyal partner, the easygoing Rick, and Rick's juvenile girlfriend Nadine, Bob plots ingenious heists and spends the rest of his days sitting around the house getting high. When the heat becomes too intense in Portland, the quartet hits the road for small-town drug stores and hospitals, but when their luck runs out it does so in grand fashion.