Inventor Flint Lockwood thought he saved the world when he destroyed his most infamous invention -- a machine that turned water into food causing cheeseburger rain and spaghetti tornadoes. But Flint soon learns that his invention survived and is now creating food-animals - "foodimals!" Flint and his friends embark on a dangerously delicious mission to battle hungry tacodiles, shrimpanzees, hippotatomuses, cheespiders and other foodimals to save the world - again!